This guide is based on my experience / experiment and my opinion! Let me know if there some change needed! Hopes this guide can help you.

Game Controls

• Move: Arrow Keys
  
• Select / Fixed Direction: Z Key
  
• Cancel / Special Attack: X key / right click
  
• Aim with mouse: left click

When you hold down Z key you character will only attack at that direction but most people probably just aim with mouse anyways...
The keybinds can be change in setting.

Stage 1
It might takes you a few tries to beat the stage but you got this!
Here some tips:

• Spend coins on upgrades (If you didn't beat it on 1st try)
  
• Try to learn enemy's attack pattern/ spawn point (Yes they spawn at the same place)
  
• Don't panic you can try to move through their gaps

Tier List

• S: Ina, Gura, Kiara (Good defense and offense)
  
• A: Watson (Skill issue)
  
• B: Caillope (Lack dmg good for clearing minions)

Basic Weapons

• S: Spider Cooking, BL Book, Glowstick (Must have)
  
• A: Elite Lava Bucket, Psycho Axe (Can kinda survive with it)
  
• B: Holo Bomb, Plug Type Asacoco (Bad on it own)

Collab Weapons

• S:
  BL Book + Psycho Axe = BL Fujoshi
  Elite Lava Bucket + Spider Cooking = Elite Cooking
  Holo Bomb + Plug Type Asacoco = Breathe In Type Asacoco
  (Best beginning collab)
  
• A:
  Elite Lava Bucket + Psycho Axe Icon = MiComet
  (Weak compares to other)

To unlock collab weapon you need to level up both weapon to 7 (max level)

Super Collab Weapon

• S: Elite Cooking + Uber Sheep = Jingisukan (Good Healing)

Farm for Coins
In the latest update you can now farm coin easily, but it will still take a while to farm. After beating Stage 1 you can now unlock Holo House, you can now fish and sell it for dust to exchange for coins. Hire manage is good too but it better to do that in late game.

Upgrade
I recommend you to upgrade:

• 1. Money Gain up, Exp Gain up, Special Attack, Fandom, Stamps, Enchantment
  
• 2. Atk up, Haste up, Speed up, Crit up, Defense up, Max Hp up
  
• 3. Anything else can buy last

• S:
  Anya (Don't move)
  Ollie (You can have unlimited death just need 10 sec CD, works even at 1 hp)
  Mumei (Aim bot)
  Roboco (Just stun them all)
  Risu (Triple Nuts)
  Aki (One shot 20 min boss)
  Onion Aqua (Speed, Dmg, HP buff & Slow enemy)
  AZKi (Self buff and Great dmg chain)
  Korone (Good def, haste, healing)
  Miko (Good buff & Aoe debuff )
  Calliope (One shot minions)
  Hachama (Good range/close Aoe, good survival kits)
  Mel (Self heal, Bats)
  Choco (Self heal, Minion)
  Kaela (Unlimited Atk boost, slow enemy)
  
• A:
  Gura (Balance)
  Mio (Good at big stage)
  Fauna (Self heal, Aim bot)
  Watson (Dog, Stop time)
  Kiara (Balance, need to move to keep passive)
  Okayu (Mogu Mogu)
  Baelz (Highest crit dmg)
  Subatu (Good Haste, Aoe passive)
  Shion (Garlic, Aoe, tp is fun but just don't tp back to enemy)
  Ayame (Good survival kits),
  
• B:
  Suisei (Pretty good crit, lack survival kits)
  Sora (Average)
  Ina (Can't die, Slow gameplay)
  Kronii (Slow gameplay)
  Fubuki (Fast and good dodge)
  Matsuri (Rhythm game, good knock back, low Dmg)
  Zeta (Good survival kits, Dmg is alright)
  Moona (Attack slow, ult is decent)
  Iofifteen (Random buff, ult is weak)
  
• C:
  Kobo (Good ult & dmg but rely getting hit and heals)
  Reine (Need coins drops, Speed debuff need Cd)
  IRYS (Good survival, bad Dmg)
  Sana (Good knock back, but bad Dmg)

• S (40 Min):
  Aqua(Good Haste, Atk, Pickup & Crit Boost)
  Anya (Special & Passive Can Cheat Many Deaths)
  
• A (35 Min):
  
  
  
• B (30 Min):
  
  
• C (Under 30 MIn):
  

• First Win! (Just win once!)
  
  
• Fubura is coming (Watch Out For Lazer Beam!) Fan Beam
  
  
• BBBRRRRRREEEEEEEEE (Don't Get Jumped!) Gorilla's Paw
  
  
• Tears of Happiness...? (Touhou Gamplay) CEO's Tears
  
  
• You have been Cursed (Hachama Chama) EN's Curse
  
  
• Thousand Mile Stare (Rat)
  
  
• Thank the Managers (<3)
  
  
• Speed Runner (Play Time Mode)
  
  
• Idol Group (Fish Farming Time)
  
  
• Power of Idols (Buy Special Attack!) Idol Costume
  
  
• Hai... (Rip... Yagoo Statue)
  
  
• Time To Upgrade (You Should Try Using Anvil) Credit Card
  
  
• Boing ( Rushia is Boing Boing!! Ummm... I Mean Use Cutting Board on Wall Type Character) Boing Boing Bounce Ball
  
  
• It's Safe I Swear (Win With Plug Type Asacoco) Drug Injection Type Asacoco
  
  
• It's Super Chat Time (Fish Farm 5000) Super Chatto Time!
  
  
• The Real Grind (Fish Farm 1,000,000)
  
  
• Wamy. (Win With Sake) Wamy Water
  
  
• Decked Out (Reach Lv. 50) Study Glasses
  
  
• Glasses are Versatile (Use Glasses in Endless to Reach Lv. 100)
  
  
• Delusional (Use Mumei Aim Bot, Beat 5000 Enemy) Halu
  
  
• Went Too Halu (Why You Max This While You Don't Have Max Upgrade?) GWS Pill
  
  
• Hamburger Country Yeah! (Eat Over 50 Burgers in One Game, Dunno if Any Type of Food Counts?)
  
  
• Thousand Milestone! (Use Calliope Special) Devil Hat
  
  
• Over Nine Thousand?! (Use Aki Passive Charge up to 10 Min Should Work/ 20 Min to be Safe)
  
  
• Couch Potato (Recommend Late Game, Use Character With Good Survival Kits: Ina, Roboco, Anya, Etc.. With Heal, Dmg Reduce Items: Breastplate, Plushie, Headphone, Etc... )
  
  
• Flesh Wound (Lose After 10 Min Once) Just Matsuri's Bandage
  
  
• I don't need it (Just Use Mumei & Win Without Using Her Special. Why Use It When You Have Aim Bot?)
  
  
• Buying Power (Win With Super Chatto Time!) Membership
  
  
• You Can Pet The Dog (Hold P on Bubba)
  
  
• Full Collab (Have 4 Collab in One Game)
  
  
• Muscle (Just Get Hit 100 Times in One Game) Breastplate
  
  
• Please Don't Fail (Enhance Collab Weapon to +1 or Maxed (Lv.7) weapon to +1 (Lv.8) ) Blacksmith's Gear
  
  
• I'm CEO now (Recommend Late Game, Endless Mode at 30 Min Beat a Yagoo )
  
  
• Payday (Random Encounter Golden Yagoo) Stolen Piggy Bank
  
  
• Free Stickers (Unlock Stamp Upgrade, Random Encounter)
  
  
• Fired (1st Try on Endless 30 Min? Nice Try >:D)
  
  
• Lucky Day (Get Super Item, Random Chance)
  
  
• Pain Peko (WTF? I DROPPED IT BY ACCIDENT!!!)
  
  
• Hardcore Gamer (Win With Hardcore Mode)
  
  
• Pay to Win (Recommend in Endless Mode: Enhance One Weapon to Lv. 10 )
  
  
• Solo Beater (Recommend Disable Weapons: Clear With Main Weapon, Once Again Just Use Aim Bot)
  
  
• True RNG (Failing Enchant 5 Times In One Game. Hint: Disable Enhance Success Rate)
  
  
• Just RNG (Failing Enchant From +1 to +2.... it has 50% Rate no????)
  
  
• Hallucinated (Win With Lv. 5 Halu... More Coins I Guess?)
  
  
• I Did It. (Face Yagoo With LV. 5 Halu in Endless Mode... Not a Good Idea...)
  
  
• Obliterated (Defeat Boss at 10 or 20 Min Under 10 Sec... Just Nuke Them With Aki Passive)
  
  
• Pacifist (Leave Mini Boss or Big Boss Alive for 5 Min Totally Not Because Can't Kill it....)
  
  
• Power Leveling (Lv up 5 Times in a Row in 1 Sec, Just Grab Rainbow Exp After Waiting a Few Min)
  
  
• Fully Loaded (Unlcok Everything in Armory)
  
  
• Thank You (Watch The Credit Fully & Be Thankful For This Amazing Game)
  
  
• Not taking any chances (Recommend in Endless Mode: Get 100% Crit, Just Use Bae & Get Crit Items)
  
  
• Millionaire (Get 1,000,000 Scores in One Game)
  
  
• Look I'm On TV (Watch TV in Stage 2 For 10 Sec)
  
  
• Don't Touch (Don't Get Hit For 5 Min, Just use Anya & Barley Move For 5 Min) Researcher's Coat
  
  
• Welcome Home! (Go to Holo House, Unlock After Winning Stage 1)
  
  
• Hey Hey (Spam on Another Holo Member Till They Get Angry)
  
  
• Harvest Time (Plant & Harvest a Crop in Holo House Garden)
  
  
• Gotta Catch'em All (Finally Got The Shiny But it Shrimp....)
  
• Thanks For The Fish (Just Walk Around or Do Something in Holo House Till Someone Fish For You)
  
  
• Dig In! (Cook a Dish at Holo House)
  
  
• Fish Fear Me (Caught 10 Fish in a Row Without Switching Fishing Rod)
  
  
• Rhythm Master (Caught 50 Fish in a Row Without Switching Fishing Rod)
  
  
• Plenty Of Fish In The Sea (Unlock Turkey or Golden Rod & Fish at Pond Till You Got Them All)
  
  
• Love Nature (Harvest Every Kind of Crop in Holo House Garden)
  
  
• Employee Of The Month (Maxed Out a Worker in Manage Hint: Hire Someone With Lowest Max Lv)
  
  
• Well Trained (Manager Maxed (Lv.4) When You Lv Up Worker it Will Manager Bar Will Increase a Little, Just Keep Fire & Hire Worker Then Lv Them up a Little)
  
  
• How Could You... (Fire a Worker & Make Them All Baqua Simp Like Me!)
  
• Highway Robbery (Collect Worker Profit When it Reach 100,000)
  
  
• Eh? (Go Behind The Holo House )
  
• Barebones (Recommend Disable Items: Win a Stage With no Item)
  
  
• It's Hammer Time (Create a Super Collab Item: Spider Cooking + Elite Lava Bucket = Elite Cooking + Uber Sheep = Jingisukan)
  
  
• Skill Issue (Turn Off Fandom & Win a Game Without Getting Character's Passive)
  
  
• Orarara (Recommend Disable Weapon and Items: Get Haste 10 Times in One Game)
  
  
• Art Block (Use Iofi Special But Don't Touch Anything)
  
  
• No Thoughts Head Empty (Win by Clicking 1st Option When Lv up)
  
  
• Bullet Hell Pro (Win & Dodge All Projectiles Like Touhou in Hard Stage)
  
  
• No Mains (Win Without Upgrade Your Main Weapon)
  
  
• Raw Strength (Win Hard Stage Without Healing Item, Just Don't Heal)
  
  
• Tank Class (Recommend Disable Weapon & Items: Have Over 500 Hp in One Game)
  
  
• Get Some Help (Need Help...)